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USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database


USC-OGP 2-DE database 
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Searching in 'USC-OGP 2-DE database' for entry matching: Q13283




USC-OGP 2-DE database:  Q13283


Q13283


General information about the entry
View entry in simple text format
Entry nameG3BP1_HUMAN
Primary accession numberQ13283
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Ras GTPase-activating protein-binding protein 1; Short=G3BP-1; EC=3.6.4.12; EC=3.6.4.13; AltName: Full=ATP-dependent DNA helicase VIII; Short=hDH VIII; AltName: Full=GAP SH3 domain-binding protein 1;.
Gene nameName=G3BP1
Synonyms=G3BP
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10}
Homo sapiens (Human)
UVEAL_MELANOMA_3-10
  map experimental info
 
UVEAL_MELANOMA_3-10

MAP LOCATIONS:
pI=5.04; Mw=21529

Cross-references
UniProtKB/Swiss-ProtQ13283; G3BP1_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameG3BP1_HUMAN
Primary accession numberQ13283
Secondary accession number(s) Q5HYE9
Sequence was last modified on November 1, 1996 (version 1)
Annotations were last modified on March 15, 2017 (version 178)
Name and origin of the protein
DescriptionRecName: Full=Ras GTPase-activating protein-binding protein 1; Short=G3BP-1; EC=3.6.4.12; EC=3.6.4.13; AltName: Full=ATP-dependent DNA helicase VIII; Short=hDH VIII; AltName: Full=GAP SH3 domain-binding protein 1;
Gene nameName=G3BP1
Synonyms=G3BP
Encoded onName=G3BP1; Synonyms=G3BP
Keywords3D-structure; Acetylation; Alternative splicing; ATP-binding; Cell membrane; Complete proteome; Cytoplasm; Direct protein sequencing; DNA-binding; Endonuclease; Helicase; Hydrolase; Membrane; Methylation; Nuclease; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; RNA-binding; Transport.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLU32519; AAB07787.1; -; mRNA
EMBLAK300098; BAG61899.1; -; mRNA
EMBLBX647869; CAI46065.1; -; mRNA
EMBLAC091982; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLBC006997; AAH06997.1; -; mRNA
CCDSCCDS4319.1; -. [Q13283-1]; .
RefSeqNP_005745.1; NM_005754.2. [Q13283-1]; .
RefSeqNP_938405.1; NM_198395.1. [Q13283-1]; .
RefSeqXP_006714812.1; XM_006714749.3. [Q13283-1]; .
RefSeqXP_006714813.1; XM_006714750.3. [Q13283-1]; .
RefSeqXP_016864411.1; XM_017008922.1. [Q13283-1]; .
RefSeqXP_016864412.1; XM_017008923.1. [Q13283-1]; .
UniGeneHs.3353; -; .
UniGeneHs.587054; -; .
PDB3Q90; X-ray; 1.70 A; A/B=1-139
PDB4FCJ; X-ray; 1.62 A; A/B=1-139
PDB4FCM; X-ray; 2.69 A; A/B=1-139
PDB4IIA; X-ray; 3.30 A; A=11-139
PDB5FW5; X-ray; 1.92 A; A/B=1-139
PDBsum3Q90; -; .
PDBsum4FCJ; -; .
PDBsum4FCM; -; .
PDBsum4IIA; -; .
PDBsum5FW5; -; .
ProteinModelPortalQ13283; -; .
SMRQ13283; -; .
BioGrid115448; 123; .
IntActQ13283; 76; .
MINTMINT-5002789; -; .
STRING9606.ENSP00000348578; -; .
iPTMnetQ13283; -; .
PhosphoSitePlusQ13283; -; .
SwissPalmQ13283; -; .
BioMutaG3BP1; -; .
DMDM14916572; -; .
EPDQ13283; -; .
PaxDbQ13283; -; .
PeptideAtlasQ13283; -; .
PRIDEQ13283; -; .
DNASU10146; -; .
EnsemblENST00000356245; ENSP00000348578; ENSG00000145907. [Q13283-1]; .
EnsemblENST00000394123; ENSP00000377681; ENSG00000145907. [Q13283-1]; .
EnsemblENST00000520177; ENSP00000427810; ENSG00000145907. [Q13283-2]; .
EnsemblENST00000522367; ENSP00000428926; ENSG00000145907. [Q13283-2]; .
GeneID10146; -; .
KEGGhsa:10146; -; .
UCSCuc063iwq.1; human. [Q13283-1]; .
CTD10146; -; .
DisGeNET10146; -; .
GeneCardsG3BP1; -; .
HGNCHGNC:30292; G3BP1; .
HPACAB037068; -; .
HPAHPA004052; -; .
MIM608431; gene; .
neXtProtNX_Q13283; -; .
OpenTargetsENSG00000145907; -; .
PharmGKBPA162389105; -; .
eggNOGKOG0116; Eukaryota; .
eggNOGENOG410YV57; LUCA; .
GeneTreeENSGT00390000011365; -; .
HOGENOMHOG000220838; -; .
HOVERGENHBG007211; -; .
InParanoidQ13283; -; .
KOK17265; -; .
OMAIMRNNAG; -; .
OrthoDBEOG091G0GAN; -; .
PhylomeDBQ13283; -; .
TreeFamTF325464; -; .
ChiTaRSG3BP1; human; .
GeneWikiG3BP1; -; .
GenomeRNAi10146; -; .
PROPR:Q13283; -; .
ProteomesUP000005640; Chromosome 5; .
BgeeENSG00000145907; -; .
CleanExHS_G3BP1; -; .
ExpressionAtlasQ13283; baseline and differential; .
GenevisibleQ13283; HS; .
GOGO:0010494; C:cytoplasmic stress granule; IEA:Ensembl; .
GOGO:0005829; C:cytosol; IDA:HPA; .
GOGO:0005925; C:focal adhesion; IDA:UniProtKB; .
GOGO:0030529; C:intracellular ribonucleoprotein complex; IBA:GO_Central; .
GOGO:0005634; C:nucleus; TAS:ProtInc; .
GOGO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0004003; F:ATP-dependent DNA helicase activity; TAS:ProtInc; .
GOGO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc; .
GOGO:0003677; F:DNA binding; IEA:UniProtKB-KW; .
GOGO:0004519; F:endonuclease activity; IEA:UniProtKB-KW; .
GOGO:0003729; F:mRNA binding; IBA:GO_Central; .
GOGO:0003723; F:RNA binding; IDA:UniProtKB; .
GOGO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl; .
GOGO:0007265; P:Ras protein signal transduction; TAS:ProtInc; .
GOGO:0006810; P:transport; IEA:UniProtKB-KW; .
CDDcd00780; NTF2; 1; .
Gene3D3.10.450.50; -; 1; .
Gene3D3.30.70.330; -; 1; .
InterProIPR002075; NTF2; .
InterProIPR032710; NTF2-like_dom; .
InterProIPR018222; Nuclear_transport_factor_2_euk; .
InterProIPR012677; Nucleotide-bd_a/b_plait; .
InterProIPR000504; RRM_dom; .
PfamPF02136; NTF2; 1; .
PfamPF00076; RRM_1; 1; .
SMARTSM00360; RRM; 1; .
SUPFAMSSF54427; SSF54427; 1; .
SUPFAMSSF54928; SSF54928; 1; .
PROSITEPS50177; NTF2_DOMAIN; 1; .
PROSITEPS50102; RRM; 1; .



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Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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